Nathalie je ne partage pas mais
respecte entièrement ton option concernant Elya car premièrement la manifestation de l'EIC chez les chiens atteints est très variable et secundo en employant un mâle INDEMNE d'EIC tu as une descendance PORTEUSE mais EXEMPTE de toute manifestation clinique puisque c'est une maladie génétique récessive, donc des chiens EN BONNE SANTE !
http://www.vdl.umn.edu/ourservices/canineneuromuscular/taylor2008/home.htmlHEREDITY
EIC is a hereditary condition, with littermates and other related dogs commonly affected. Clinically unaffected dams and sires commonly produce litters with more than one affected dog and pedigree analysis strongly
supports an autosomal recessive mode of inheritance.
DNA harvested from the blood of affected dogs and their relatives was used to perform a full genome scan at the University of Minnesota in order to identify a genetic marker for EIC, and to find the genetic mutation causing EIC. In 2007 the chromosomal locus (site) of the mutation was found on chromosome 9, and the genetic mutation responsible for susceptibility to EIC was identified. This is a mutation in the gene for dynamin-1, a protein expressed only in the brain and spinal cord where it plays a key role in forming synaptic vesicles containing neurotransmitters. DNM1 is not required during low level neurological stimulation, but when a heightened stimulus creates a heavy load on release of CNS neurotransmitters (as with intense exercise, a high level of excitement and perhaps increased body temperature) DNM1 is essential for sustained synaptic transmission in the brain and spinal cord.